51012-33-0
51012-33-0
Chemical Structure
Tiapride hydrochloride
- CAS No.: 51012-33-0
- Formula:C15H25ClN2O4S
- Molecular Weight:364.89
IUPAC Name: N-(2-(diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)benzamide hydrochloride
InChIKey: OTFDPNXIVHBTKW-UHFFFAOYSA-N
SMILES: O=C(NCCN(CC)CC)C1=CC(S(=O)(C)=O)=CC=C1OC.[H]Cl
Biological Activity: Tiapride hydrochloride is a selective and orally active D2 and D3 dopamine receptors antagonist with IC50 values of 110-320 nM and 180 nM, respectively. Tiapride hydrochloride shows anti-dyskinetic activity and anxiolytic activity. Tiapride hydrochloride is a neuroleptic agent[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Tiapride hydrochloride | 99.95% | Tiapride hydrochloride is a selective and orally active D2 and D3 dopamine receptors antagonist with IC50 values of 110-320 nM and 180 nM, respectively. Tiapride hydrochloride shows anti-dyskinetic activity and anxiolytic activity. Tiapride hydrochloride is a neuroleptic agent. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Tiapride hydrochloride (Standard) | ≥98% | Tiapride (hydrochloride) (Standard) is the analytical standard of Tiapride (hydrochloride). This product is intended for research and analytical applications. Tiapride hydrochloride is a selective and orally active D2 and D3 dopamine receptors antagonist with IC50 values of 110-320 nM and 180 nM, respectively. Tiapride hydrochloride shows anti-dyskinetic activity and anxiolytic activity. Tiapride hydrochloride is a neuroleptic agent. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Scatton B, et al. The preclinical pharmacologic profile of tiapride. Eur Psychiatry. 2001 Jan;16 Suppl 1:29s-34s. [Content Brief]
- [2]. Peters DH, et al. Tiapride. A review of its pharmacology and therapeutic potential in the management of alcohol dependence syndrome. Drugs. 1994 Jun;47(6):1010-32. [Content Brief]
