520-42-3
520-42-3
Chemical Structure
Asebogenin
- CAS No.: 520-42-3
- Formula:C16H16O5
- Molecular Weight:288.30
IUPAC Name: 1-(2,6-dihydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one
InChIKey: UPXIBKPHJYQSGP-UHFFFAOYSA-N
SMILES: O=C(C1=C(O)C=C(OC)C=C1O)CCC2=CC=C(O)C=C2
Biological Activity: Asebogenin has antimalarial activity in vitro[1]. Asebogenin can inhibit the phosphorylation of Syk, thereby effectively suppressing platelet activation and the formation of neutrophil extracellular traps[2].
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Asebogenin | Asebogenin has antimalarial activity in vitro. Asebogenin can inhibit the phosphorylation of Syk, thereby effectively suppressing platelet activation and the formation of neutrophil extracellular traps. | |||||||||||||||||||||
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References
- [1]. 1.Jenett-Siems K, et al. n vitro antiplasmodial activity of Central American medicinal plants. Trop Med Int Health. 1999 Sep;4(9):611-5. [Content Brief]
- [2]. Li L, et al. Asebogenin suppresses thrombus formation via inhibition of Syk phosphorylation. Br J Pharmacol. 2023 Feb;180(3):287-307. [Content Brief]
Keywords
