5231-60-7
5231-60-7
Chemical Structure
Vindorosine
Synonym(s): Demethoxyvindoline
- CAS No.: 5231-60-7
- Formula:C24H30N2O5
- Molecular Weight:426.51
IUPAC Name: (3aR,3a1R,4R,5S,5aR,10bR)-methyl 4-acetoxy-3a-ethyl-5-hydroxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate
InChIKey: SASWULSUPROHRT-MCIGMTSASA-N
SMILES: CN1C2=CC=CC=C2[C@@]3(CC4)[C@]1([H])[C@](C(OC)=O)(O)[C@H](OC(C)=O)[C@@]5(CC)[C@]3([H])N4CC=C5
Biological Activity: Vindorosine is an alkaloid from Catharanthus trichophyllus Roots. Vindorosine relaxes renal arteries[1][2].
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Vindorosine | Vindorosine is an alkaloid from Catharanthus trichophyllus Roots. Vindorosine relaxes renal arteries. | |||||||||||||||||||||
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References
- [1]. Cordell GA, et al. Catharanthus alkaloids XXXII: isolation of alkaloids from Catharanthus trichophyllus roots and structure elucidation of cathaphylline. J Pharm Sci. 1976 Mar;65(3):366-9. [Content Brief]
- [2]. Wu XL, et al. Antagonism of Ca2+ influx via L-type Ca2+ channels mediates the vasorelaxant effect of Catharanthus roseus-derived vindorosine in rat renal artery. Planta Med. 2014 Dec;80(18):1672-7. [Content Brief]
Keywords
