526-43-2
526-43-2
Chemical Structure
Rhetsinine
- CAS No.: 526-43-2
- Formula:C19H17N3O2
- Molecular Weight:319.36
InChIKey: RAEOYMOPVHBBKE-UHFFFAOYSA-N
SMILES: O=C(N1C(C2=C(CC1)C3=C(C=CC=C3)N2)=O)C4=C(NC)C=CC=C4
Biological Activity: Rhetsinine is an aldose reductase inhibitor isolated from Evodia rutaecarpa, exhibiting an IC50 value of 24.1 μM. At a concentration of 100 μM, rhetsinine significantly inhibits sorbitol accumulation by 79.3%. This compound shows potential for research in diabetic complications, including diabetic neuropathy and retinopathy[1].
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Rhetsinine | Rhetsinine is an aldose reductase inhibitor isolated from Evodia rutaecarpa, exhibiting an IC50 value of 24.1 μM. At a concentration of 100 μM, rhetsinine significantly inhibits sorbitol accumulation by 79.3%. This compound shows potential for research in diabetic complications, including diabetic neuropathy and retinopathy. | |||||||||||||||||||||
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