53587-29-4
53587-29-4
Chemical Structure
L-DOPA-2,5,6-d3
- CAS No.: 53587-29-4
- Formula:C9H8D3NO4
- Molecular Weight:200.21
IUPAC Name: (S)-2-amino-3-(3,4-dihydroxyphenyl-2,5,6-d3)propanoic acid
InChIKey: WTDRDQBEARUVNC-UOCCHMHCSA-N
SMILES: C([C@@H](C(O)=O)N)C1=C(C(O)=C(O)C(=C1[2H])[2H])[2H]
Biological Activity: L-DOPA-2,5,6-d3 is the deuterium labeled L-DOPA. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
L-DOPA-2,5,6-d3 | 99.94% | L-DOPA-2,5,6-d3 is the deuterium labeled L-DOPA. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
L-DOPA (Standard) | 99.86% | L-DOPA (Standard) is the analytical standard of L-DOPA. This product is intended for research and analytical applications. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
L-DOPA-15N | L-DOPA-15N (Levodopa-15N) is the 15N-labeled L-DOPA (HY-N0304). L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
L-DOPA-13C | 99.77% | L-DOPA-13C is the 13C labeled L-DOPA. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
L-DOPA-d6 | 99.48% | L-DOPA-d6 is the deuterium labeled L-DOPA. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
L-DOPA-13C6 | 99.11% | L-DOPA-13C6 is the 13C-labled L-DOPA. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
SD-1077 | SD-1077 is a selectively deuterated precursor of dopamine (DA). SD-1077 can be used for the study of Parkinson's disease. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
L-DOPA | 99.98% | L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 1.00
HY-113404DL-Dopa -
Similarity Score 1.00
HY-113404S1L-Dopa-d3 -
Similarity Score 1.00
HY-W096171D-Dopa -
Similarity Score 0.93
HY-N0473S9L-Tyrosine-d7 -
Similarity Score 0.93
HY-W015007SMetyrosine-13C9,15N,d7 -
Similarity Score 0.93
HY-Y0123S1DL-Tyrosine-d7 -
Similarity Score 0.93
HY-Y0444S2D-Tyrosine-d7 -
Similarity Score 0.92
HY-N0473SL-Tyrosine-d4 -
Similarity Score 0.92
HY-Y0123S4DL-Tyrosine-d4 -
Explore the MedChemAI to find more analogs
References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Hyland K, et al. Aromatic L-amino acid decarboxylase deficiency: diagnostic methodology. Clin Chem. 1992 Dec;38(12):2405-10. [Content Brief]
- [3]. Merims D, et al. Dopamine dysregulation syndrome, addiction and behavioral changes in Parkinson's disease. Parkinsonism Relat Disord. 2008;14(4):273-80. Epub 2007 Nov 7. [Content Brief]
