536748-46-6
536748-46-6
Chemical Structure
Eribaxaban
Synonym(s): PD-0348292
- CAS No.: 536748-46-6
- Formula:C24H22ClFN4O4
- Molecular Weight:484.91
IUPAC Name: (2R,4R)-N1-(4-chlorophenyl)-N2-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidine-1,2-dicarboxamide
InChIKey: QQBKAVAGLMGMHI-WIYYLYMNSA-N
SMILES: O=C(NC(C=C1)=CC=C1Cl)N2[C@H](C[C@@H](OC)C2)C(NC3=CC=C(C=C3F)N(C=CC=C4)C4=O)=O
Biological Activity: Eribaxaban (PD-0348292) is an orally active and selective FXa inhibitor with a Ki value of 0.32 nM. Eribaxaban reduces thrombus formation[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Eribaxaban | 98.52% | Eribaxaban (PD-0348292) is an orally active and selective FXa inhibitor with a Ki value of 0.32 nM. Eribaxaban reduces thrombus formation. | ||||||||||||||||||||
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References
- [1]. Eriksson BI, et al. Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in development. Clin Pharmacokinet. 2009;48(1):1-22. [Content Brief]
- [2]. Karnicki K, et al. Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis. Thromb Haemost. 2008 Apr;99(4):759-66. [Content Brief]
Keywords
