57530-40-2
57530-40-2
Chemical Structure
Ethacizine hydrochloride
Synonym(s): Ethacizin; NIK-244
- CAS No.: 57530-40-2
- Formula:C22H28ClN3O3S
- Molecular Weight:449.99
IUPAC Name: ethyl (10-(3-(diethylamino)propanoyl)-10H-phenothiazin-2-yl)carbamate hydrochloride
InChIKey: VHNXQKLWIQHSOY-UHFFFAOYSA-N
SMILES: O=C(OCC)NC(C=C1N2C(CCN(CC)CC)=O)=CC=C1SC3=C2C=CC=C3.[H]Cl
Biological Activity: Ethacizine hydrochloride (Ethacizin) is an antiarrhythmic agent and analog of Ethmozine (HY-B0615A). Ethacizine hydrochloride inhibits ventricular premature beats[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Ethacizine hydrochloride | 99.25% | Ethacizine hydrochloride (Ethacizin) is an antiarrhythmic agent and analog of Ethmozine (HY-B0615A). Ethacizine hydrochloride inhibits ventricular premature beats. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Ethacizine hydrochloride (Standard) | ≥98% | Ethacizine hydrochloride (Standard) (Ethacizin (Standard)) is the analytical standard of Ethacizine hydrochloride (HY-135121). This product is intended for research and analytical applications. Ethacizine hydrochloride (Ethacizin) is an antiarrhythmic agent and analog of Ethmozine (HY-B0615A). Ethacizine hydrochloride inhibits ventricular premature beats. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.98
HY-131987Ethacizine -
Similarity Score 0.78
HY-B0615AMoricizine Hydrochloride -
Similarity Score 0.74
HY-121215Chloracyzine -
Similarity Score 0.66
HY-B0615ASMoricizine-d8 Hydrochloride -
Similarity Score 0.64
HY-110249CINPA1 -
Similarity Score 0.62
HY-110411Chlorproethazine hydrochloride -
Similarity Score 0.59
HY-123721Tiracizine hydrochloride -
Similarity Score 0.58
HY-187043Methopromazine maleate -
Similarity Score 0.58
HY-119913ADacemazine hydrochloride -
Explore the MedChemAI to find more analogs
References
- [1]. Smetnev AS, et al. Clinical, electrophysiologic and antiarrhythmic efficacy of moricizine HCl. The American journal of cardiology. 1987 Oct 16;60(11):40F-44F.
- [2]. Baldenkov GN, et al. Action of ethmozine and ethacizine on dopaminergic adenylate cyclase of the brain striatal system. Bulletin of Experimental Biology and Medicine. 1984 Oct;98(4):1377-80.
- [3]. Kukes VG, et al. A new Soviet drug, ethacizine, in the treatment of ventricular rhythm disorders. Kardiologiia. 1983 Nov;23(11):45-7. Russian.
- [4]. Karaush AP, et al. Effectiveness of single intravenous administration of cordarone, ethacizine and obsidan in ventricular extrasystole in patients with chronic alcoholism during withdrawal. Kardiologiia. 1991 Jan;31(1):65-6. Russian.
