5812-07-7
5812-07-7
Chemical Structure
SU4312
- CAS No.: 5812-07-7
- Formula:C17H16N2O
- Molecular Weight:264.32
IUPAC Name: (Z)-3-(4-(dimethylamino)benzylidene)indolin-2-one
InChIKey: UAKWLVYMKBWHMX-PTNGSMBKSA-N
SMILES: O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=C(N(C)C)C=C3
Biological Activity: SU4312 is the racemate of (Z)-SU4312 and (E)-SU4312. (Z)-SU4312 inhibits PDGFR and FLK-1 with IC50s of 19.4 and 0.8 μM, respectively. (E)-SU4312 inhibits PDGFR, FLK-1, EGFR, HER-2, and IGF-1R with IC50s of 24.2, 5.2, 18.5, 16.9 and 10.0 μM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SU4312 | 99.74% | SU4312 is the racemate of (Z)-SU4312 and (E)-SU4312. (Z)-SU4312 inhibits PDGFR and FLK-1 with IC50s of 19.4 and 0.8 μM, respectively. (E)-SU4312 inhibits PDGFR, FLK-1, EGFR, HER-2, and IGF-1R with IC50s of 24.2, 5.2, 18.5, 16.9 and 10.0 μM, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
