2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. SU5205

SU5205 

Cat. No.: HY-21289 Purity: 98.44%
COA Handling Instructions

SU5205 is an inhibitor of VEGFR2 (FLK-1), with an IC50 of 9.6 μM.

For research use only. We do not sell to patients.

SU5205 Chemical Structure

SU5205 Chemical Structure

CAS No. : 3476-86-6

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 55 In-stock
Estimated Time of Arrival: December 31
Solid
50 mg USD 50 In-stock
Estimated Time of Arrival: December 31
100 mg USD 80 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

View All VEGFR Isoform Specific Products:

View All Isoforms
VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

SU5205 is an inhibitor of VEGFR2 (FLK-1), with an IC50 of 9.6 μM[1].

IC50 & Target[1]

Flk-1

9.6 μM (IC50)

In Vitro

SU5205 inhibits ligand-induced endothelial mitogenesis for VEGF with an IC50 of 5.1 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

239.24

Appearance

Solid

Formula

C15H10FNO
CAS No.
SMILES

O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=C(F)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (1044.98 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1799 mL 20.8995 mL 41.7990 mL
5 mM 0.8360 mL 4.1799 mL 8.3598 mL
10 mM 0.4180 mL 2.0900 mL 4.1799 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

SU52053476-86-6SU 5205SU-5205VEGFRVascular endothelial growth factor receptorVEGFR2FLK-1endothelialmitogenesisInhibitorinhibitorinhibit

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