2. SU5205

SU5205 is an inhibitor of VEGFR2 (FLK-1), with an IC50 of 9.6 μM.

For research use only. We do not sell to patients.

SU5205 Chemical Structure

SU5205 Chemical Structure

CAS No. : 3476-86-6

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 55 In-stock
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Solid
50 mg USD 50 In-stock
100 mg USD 80 In-stock
200 mg   Get quote  
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SU5205 Related Antibodies

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Description

SU5205 is an inhibitor of VEGFR2 (FLK-1), with an IC50 of 9.6 μM[1].

IC50 & Target

IC50: 9.6 μM (VEGFR2 FLK-1)[1]
In Vitro

SU5205 inhibits ligand-induced endothelial mitogenesis for VEGF with an IC50 of 5.1 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SU5205 Related Antibodies
Molecular Weight

239.24

Formula

C15H10FNO
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=C(F)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (1044.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1799 mL 20.8995 mL 41.7990 mL
5 mM 0.8360 mL 4.1799 mL 8.3598 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.1799 mL 20.8995 mL 41.7990 mL 104.4976 mL
5 mM 0.8360 mL 4.1799 mL 8.3598 mL 20.8995 mL
10 mM 0.4180 mL 2.0900 mL 4.1799 mL 10.4498 mL
15 mM 0.2787 mL 1.3933 mL 2.7866 mL 6.9665 mL
20 mM 0.2090 mL 1.0450 mL 2.0900 mL 5.2249 mL
25 mM 0.1672 mL 0.8360 mL 1.6720 mL 4.1799 mL
30 mM 0.1393 mL 0.6967 mL 1.3933 mL 3.4833 mL
40 mM 0.1045 mL 0.5225 mL 1.0450 mL 2.6124 mL
50 mM 0.0836 mL 0.4180 mL 0.8360 mL 2.0900 mL
60 mM 0.0697 mL 0.3483 mL 0.6967 mL 1.7416 mL
80 mM 0.0522 mL 0.2612 mL 0.5225 mL 1.3062 mL
100 mM 0.0418 mL 0.2090 mL 0.4180 mL 1.0450 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SU52053476-86-6SU 5205SU-5205Inhibitorinhibitorinhibit

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