58293-56-4
Chemical Structure
DCVJ
Synonym(s): 9-(2,2-Dicyanovinyl)julolidine
- CAS No.: 58293-56-4
- Formula:C16H15N3
- Molecular Weight:249.31
IUPAC Name: (E)-4-(2-(6-(didodecylamino)naphthalen-2-yl)vinyl)-1-(3-(trimethylammonio)propyl)pyridin-1-ium bromide
InChIKey: LROAUBRDKLVBCP-UHFFFAOYSA-N
SMILES: N#C/C(C#N)=C/C1=CC(CCCN2CCC3)=C2C3=C1
Biological Activity: DCVJ (9-(2,2-Dicyanovinyl)julolidine), a molecular rotor and unique fluorescent dye, binds to tubulin and actin, and increases its fluorescence intensity drastically upon polymerization. DCVJ also binds to phospholipid bilayers and increases its fluorescence intensity. DCVJ can detect the kinetic process of degranulation of mast cells (Absorption/emission=489/505 nm)[1][2].
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DCVJ | 99.48% | DCVJ (9-(2,2-Dicyanovinyl)julolidine), a molecular rotor and unique fluorescent dye, binds to tubulin and actin, and increases its fluorescence intensity drastically upon polymerization. DCVJ also binds to phospholipid bilayers and increases its fluorescence intensity. DCVJ can detect the kinetic process of degranulation of mast cells (Absorption/emission=489/505 nm). | ||||||||||||||||||||
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- [1]. Furuno T, et al. A fluorescent molecular rotor probes the kinetic process of degranulation of mast cells. Immunol Lett. 1992;33(3):285-288. [Content Brief]
- [2]. Haidekker MA, et al. New fluorescent probes for the measurement of cell membrane viscosity. Chem Biol. 2001 Feb;8(2):123-31. [Content Brief]
Keywords
