59-26-7
59-26-7
Chemical Structure
Nikethamide
Synonym(s): N,N-Diethylnicotinamide
- CAS No.: 59-26-7
- Formula:C10H14N2O
- Molecular Weight:178.23
IUPAC Name: N,N-diethylnicotinamide
InChIKey: NCYVXEGFNDZQCU-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CN=C1)N(CC)CC
Biological Activity: Nikethamide (N,N-Diethylnicotinamide), one of the respiratory central stimulants, has the potential for respiratory failure research[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nikethamide | 99.87% | Nikethamide (N,N-Diethylnicotinamide), one of the respiratory central stimulants, has the potential for respiratory failure research. | ||||||||||||||||||||
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Nikethamide (Standard) | ≥98% | Nikethamide (Standard) is the analytical standard of Nikethamide. This product is intended for research and analytical applications. Nikethamide, one of the respiratory central stimulants, has the potential for respiratory failure research. | ||||||||||||||||||||
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N,N-Diethylbenzamide | 96.26% | N,N-Diethylbenzamide (Benzoyldiethylamine) is a mosquito repellent with highly effective mosquito-repellent properties. | ||||||||||||||||||||
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ω-Hydroxy-DEET | 96.0% | ω-Hydroxy-DEET is a major metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). ω-Hydroxy-DEET has anti-proliferative effects. DEET is a spatial repellent and an irritant that commonly used to prevent contact with mosquitoes. | ||||||||||||||||||||
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Propyl nicotinate | Propyl nicotinate (Nicotinic acid propyl ester), the propyl ester of niacin, occurs in various animal and plant tissues, where it contributes to the formation of the coenzymes NAD and NADP. | |||||||||||||||||||||
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Diethyltoluamide | 98.64% | Diethyltoluamide (DEET) is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects. Diethyltoluamide is toxic to hepatocytes and can lead to many physiological, pharmacological, and behavioral abnormalities, particularly motor deficits and learning and memory dysfunction. | ||||||||||||||||||||
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N-Ethylnicotinamide | 99.52% | N-Ethylnicotinamide is a compound with weak vasodilatory activity. N-Ethylnicotinamide also serves as the core scaffold of the antianginal agent Nicorandil (HY-B0341) and its derivatives. | ||||||||||||||||||||
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NSC 404988 | NSC 404988 (N,N-Diethyl-4-chlorobenzamide) is a cyclic acetal that can be used for the fluorination reaction. | |||||||||||||||||||||
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N,N-Diethyl-p-toluamide | N,N-Diethyl-p-toluamide is an active compound. | |||||||||||||||||||||
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N-Methoxy-N-methylnicotinamide-13C6 | N-Methoxy-N-methylnicotinamide-13C6 (3-Pyridinecarboxamide, N-methoxy-N-methyl-13C6) is the 13C-labeled N-methoxy-N-methylnicotinamide (HY-W051270). | |||||||||||||||||||||
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Ethyl nicotinate hydrochloride-13C6 | Ethyl nicotinate hydrochloride-13C6 (Nicotinic acid ethylester hydrochloride-13C6) is the 13C-labeled Ethyl nicotinate (HY-W013628). | |||||||||||||||||||||
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Nicotinamide impurity 4 | Nicotinamide impurity 4 is an impurity of Nicotinamide (HY-B0150). | |||||||||||||||||||||
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References
- [1]. Chen L, et al. Simultaneous determination of nikethamide and lidocaine in human blood and cerebrospinal fluid by high performance liquid chromatography. J Pharm Biomed Anal. 2007 Apr 11;43(5):1757-62. [Content Brief]
- [2]. Koldaev VM. Effect of ephedrine and nikethamide on the outcome of microwave lesions in mice. Bull Exp Biol Med. 1974 Sep;77(3):298-301. [Content Brief]
- [3]. Dulfano M J, et al. Nikethamide as a respiratory analeptic[J]. JAMA, 1963, 185(2): 69-74.
- [4]. MCNICOL MW, et al. Nikethamide for severe CO2 retention in exacerbations of chronic bronchitis. Br Med J. 1963 Mar 9;1(5331):646-8. [Content Brief]
