59458-27-4
Chemical Structure
Ficellomycin
Synonym(s): U-47929
- CAS No.: 59458-27-4
- Formula:C13H24N6O3
- Molecular Weight:312.37
IUPAC Name: 2-((S)-2-amino-3-methylbutanamido)-2-((2S,4S,5S)-4-guanidino-1-azabicyclo[3.1.0]hexan-2-yl)acetic acid
InChIKey: DGIHWRUPUISVIZ-MGDZAPLHSA-N
SMILES: [H][C@]1(C[C@@H]([C@@H]2CN21)NC(N)=N)C(C(O)=O)NC([C@H](C(C)C)N)=O
Biological Activity:
Ficellomycin is a nitrogen-containing bicyclic antibiotic with strong activity against Gram-positive bacteria, including multidrug-resistant strains of Staphylococcus aureus. Ficellomycin works by inducing the formation of defective 34S DNA fragments, which interfere with the semi-conservative DNA replication process. These fragments lack the ability to integrate into larger DNA segments and eventually form a complete bacterial chromosome. Ficellomycin can be used in research for various bacterial diseases[1].
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Ficellomycin | Ficellomycin is a nitrogen-containing bicyclic antibiotic with strong activity against Gram-positive bacteria, including multidrug-resistant strains of Staphylococcus aureus. Ficellomycin works by inducing the formation of defective 34S DNA fragments, which interfere with the semi-conservative DNA replication process. These fragments lack the ability to integrate into larger DNA segments and eventually form a complete bacterial chromosome. Ficellomycin can be used in research for various bacterial diseases. |
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Keywords
