5950-12-9
5950-12-9
Chemical Structure
Piperlonguminine
- CAS No.: 5950-12-9
- Formula:C16H19NO3
- Molecular Weight:273.33
IUPAC Name: (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-N-isobutylpenta-2,4-dienamide
InChIKey: WHAAPCGHVWVUEX-GGWOSOGESA-N
SMILES: O=C(NCC(C)C)/C=C/C=C/C1=CC=C(OCO2)C2=C1
Biological Activity: Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows various biological properties, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities[1][2][3][4].
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Piperlonguminine | 99.81% | Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows various biological properties, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities. | ||||||||||||||||||||
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Piperlonguminine (Standard) | ≥98% | Sotalol (hydrochloride) (Standard) is the analytical standard of Sotalol (hydrochloride). This product is intended for research and analytical applications. Sotalol hydrochloride (MJ 1999) is an orally active, non-selective β-adrenergic receptor blocker. Sotalol hydrochloride is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol hydrochloride blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent. | ||||||||||||||||||||
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References
- [1]. Bezerra DP, et, al. In vivo growth inhibition of sarcoma 180 by piperlonguminine, an alkaloid amide from the Piper species. J Appl Toxicol. 2008 Jul; 28(5): 599-607. [Content Brief]
- [2]. Yang T, et, al. Piperlonguminine is neuroprotective in experimental rat stroke. Int Immunopharmacol. 2014 Dec; 23(2): 447-51. [Content Brief]
- [3]. Marques JV, et, al. Antifungal amides from Piper scutifolium and Piper hoffmanseggianum. J Nat Prod. 2007 Dec; 70(12):2036-9. [Content Brief]
- [4]. Chy MNU, et, al. Antibacterial, anthelmintic, and analgesic activities of Piper sylvaticum (Roxb.) leaves and in silico molecular docking and PASS prediction studies of its isolated compounds. J Complement Integr Med. 2019 Aug 22;16(4). [Content Brief]
