5984-59-8
Chemical Structure
Octodrine hydrochloride
Synonym(s): 2-Amino-6-methylheptane hydrochloride; 1,5-Dimethylhexylamine hydrochloride; 6-Methyl-2-heptylamine hydrochloride
- CAS No.: 5984-59-8
- Formula:C8H20ClN
- Molecular Weight:165.70
IUPAC Name: 6-methylheptan-2-amine hydrochloride
InChIKey: JWQWFYMPBWLERY-UHFFFAOYSA-N
SMILES: CC(N)CCCC(C)C.[H]Cl
Biological Activity: Octodrine hydrochloride (2-Amino-6-methylheptane hydrochloride; 1,5-Dimethylhexylamine hydrochloride; 6-Methyl-2-heptylamine hydrochloride) is a sympathomimetic amine that induces pressor effects and central nervous system stimulation. Octodrine hydrochloride agonizes estrogen receptor α (ERα) and exhibits antimicrobial activity. Octodrine hydrochloride kills Candida albicans grown in serum and kills uropathogenic Escherichia coli persister cells. Octodrine hydrochloride triggers biphasic cardiac effects, reduces spontaneous locomotor activity, and alters neuronal activity and stress-related gene expression after acute exposure in zebrafish larvae. Octodrine hydrochloride can be used in research on fungal infections, bacterial infections, and hypotension[1][2][3][4][5][6][7].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Octodrine hydrochloride | 98.0% | Octodrine hydrochloride (2-Amino-6-methylheptane hydrochloride; 1,5-Dimethylhexylamine hydrochloride; 6-Methyl-2-heptylamine hydrochloride) is a sympathomimetic amine that induces pressor effects and central nervous system stimulation. Octodrine hydrochloride agonizes estrogen receptor α (ERα) and exhibits antimicrobial activity. Octodrine hydrochloride kills Candida albicans grown in serum and kills uropathogenic Escherichia coli persister cells. Octodrine hydrochloride triggers biphasic cardiac effects, reduces spontaneous locomotor activity, and alters neuronal activity and stress-related gene expression after acute exposure in zebrafish larvae. Octodrine hydrochloride can be used in research on fungal infections, bacterial infections, and hypotension. | ||||||||||||||||||||
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References
- [1]. Cohen PA, et al. Four experimental stimulants found in sports and weight loss supplements: 2-amino-6-methylheptane (octodrine), 1,4-dimethylamylamine (1,4-DMAA), 1,3-dimethylamylamine (1,3-DMAA) and 1,3-dimethylbutylamine (1,3-DMBA). Clinical toxicology (Philadelphia, Pa.). 2018 Jun;56(6):421-426.
- [2]. Kim K, et al. Repurposing FDA approved drugs against the human fungal pathogen, Candida albicans. Annals of clinical microbiology and antimicrobials. 2015 Jun 09;14:32.
- [3]. Imade RO, et al. Chemical characterization, safety profile and antileiomyoma effects of Tetrapleura tetraptera Taubert (Fabaceae) fruit ethanol extract in Sprague Dawley rats. Future Journal of Pharmaceutical Sciences. 2024 Mar 15;10(1):41.
- [4]. Wall G, et al. Screening Repurposing Libraries for Identification of Drugs with Novel Antifungal Activity. Antimicrobial agents and chemotherapy. 2020 Aug 20;64(9):e00924-20.
- [5]. Niu H, et al. Identification of Anti-Persister Activity against Uropathogenic Escherichia coli from a Clinical Drug Library. Antibiotics (Basel, Switzerland). 2015 May 12;4(2):179-87.
- [6]. Carrão-Dantas EK. Acute Octodrine (DMHA) Exposure Disrupts Cardiac Function, Locomotor Activity, and Neuronal Activity–Responsive Transcription in Zebrafish Larvae.
- [7]. Nwokwu C, et al. Anticancer screening and GC‑MS metabolite profiling of endemic southwest Florida flora: Evaluating the therapeutic potential of three tropical species against Glioblastoma Multiforme. Tropical Journal of Pharmaceutical Research, 2026, 25(6): 745-760.
