6005-18-1
6005-18-1
Chemical Structure
Dihydrosamidin
Synonym(s): Dimidin
- CAS 番号: 6005-18-1
- Formula:C21H24O7
- Molecular Weight:388.41
InChIKey: ALKTVPFKDYZFGA-WOJBJXKFSA-N
SMILES: CC(O[C@@H]1C2=C(OC(C)([C@@H]1OC(CC(C)C)=O)C)C=CC(C=C3)=C2OC3=O)=O
Biological Activity: Dihydrosamidin is a coumarin component isolated from the fruits of ammi visnaga. Dihydrosamidin promotes neuroplasticity, modulates glycolysis and oxidative phosphorylation and enhances antioxidant defences. Dihydrosamidin inhibits triacylglycerol accumulation in 3T3-L1 preadipocytes. Dihydrosamidin can be used for neuroprotective, anti-obesity study[1][2][3].
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Dihydrosamidin | Dihydrosamidin is a coumarin component isolated from the fruits of ammi visnaga. Dihydrosamidin promotes neuroplasticity, modulates glycolysis and oxidative phosphorylation and enhances antioxidant defences. Dihydrosamidin inhibits triacylglycerol accumulation in 3T3-L1 preadipocytes. Dihydrosamidin can be used for neuroprotective, anti-obesity study. | |||||||||||||||||||||
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References
- [1]. Winderl B, et al. Fast and improved separation of major coumarins in Ammi visnaga (L.) Lam. by supercritical fluid chromatography. J Sep Sci. 2016 Oct;39(20):4042-4048. [Content Brief]
- [2]. Toropova AA, et al. Dihydrosamidin: the basic khellactone ester derived from Phlojodicarpus komarovii and its impact on neurotrophic factors, energy and antioxidant metabolism after rat cerebral ischemia-reperfusion injury. Nat Prod Res. 2024 Nov 27:1-6. [Content Brief]
- [3]. Olennikov DN, et al. Khellactone Derivatives and Other Phenolics of Phlojodicarpus sibiricus (Apiaceae): HPLC-DAD-ESI-QQQ-MS/MS and HPLC-UV Profile, and Antiobesity Potential of Dihydrosamidin. Molecules. 2019 Jun 19;24(12):2286. [Content Brief]
