60111-76-4
60111-76-4
Chemical Structure
Boc-D-Leu-Osu
- CAS No.: 60111-76-4
- Formula:C15H24N2O6
- Molecular Weight:328.36
IUPAC Name: 2,5-dioxopyrrolidin-1-yl (tert-butoxycarbonyl)-D-leucinate
InChIKey: WXRGJQZMGGGTSS-SNVBAGLBSA-N
SMILES: CC(C)(C)OC(N[C@H](CC(C)C)C(ON1C(CCC1=O)=O)=O)=O
Biological Activity: Boc-D-Leu-OSu is an amino acids building block. Boc-D-Leu-OSu can be used to synthesize analogues of gastrin antagonist and antibiotic Gramicidin S[1][2].
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Boc-D-Leu-Osu | Boc-D-Leu-OSu is an amino acids building block. Boc-D-Leu-OSu can be used to synthesize analogues of gastrin antagonist and antibiotic Gramicidin S. | |||||||||||||||||||||
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References
- [1]. Rodriguez M, et al. Synthesis of gastrin antagonists, analogues of the C-terminal tetrapeptide of gastrin, by introduction of a beta-homo residue. J Med Chem. 1989 Mar;32(3):522-8. [Content Brief]
- [2]. Sato, et al. Design and Synthesis of Gramicidin S Analogs with High Antibiotic Activity.Bulletin of the Chemical Society of Japan, 2013, 86(1):112-120.
