6013-57-6
6013-57-6
Chemical Structure
Arecaidine hydrobromide
- CAS No.: 6013-57-6
- Formula:C7H12BrNO2
- Molecular Weight:222.08
IUPAC Name: 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid hydrobromide
InChIKey: BZFFCPUUBJMUSS-UHFFFAOYSA-N
SMILES: O=C(C1=CCCN(C)C1)O.[H]Br
Biological Activity: Arecaidine hydrobromide, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrobromide is a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Arecaidine hydrobromide | 98.0% | Arecaidine hydrobromide, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrobromide is a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Arecaidine-d5 hydrobromide | Arecaidine-d5 hydrobromide is the deuterium labeled Arecaidine hydrobromide (HY-N2368B). Arecaidine hydrobromide, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrobromide is a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. D Lodge, et al. Effects of the Areca nut constituents arecaidine and guvacine on the action of GABA in the cat central nervous system. Brain Res. 1977 Nov 18;136(3):513-22. [Content Brief]
- [2]. Valerie Voigt, et al. Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1). J Pharm Pharmacol. 2013 Apr;65(4):582-90. [Content Brief]
