Arecaidine hydrobromide
Based on 1 publication(s) in Google Scholar
Arecaidine hydrobromide, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrobromide is a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 6013-57-6
- Formula: C7H12BrNO2
- Molecular Weight:222.08
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Arecaidine hydrobromide
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Biological Activity
Chemical Information
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CAS No. 6013-57-6
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Appearance Solid
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Molecular Weight 222.08
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Formula C7H12BrNO2
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Color White to off-white
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SMILES
O=C(C1=CCCN(C)C1)O.[H]Br
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Int J Mol Sci
Oxidative Stress and Endoplasmic Reticulum Stress Contributes to Arecoline and Its Secondary Metabolites-Induced Dyskinesia in Zebrafish Embryos. [Abstract]2023 Mar 28;24(7):6327. PMID: 37047326
Solvent & Solubility
H2O : 100 mg/mL (450.29 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. D Lodge, et al. Effects of the Areca nut constituents arecaidine and guvacine on the action of GABA in the cat central nervous system. Brain Res. 1977 Nov 18;136(3):513-22. [Content Brief]
[2]. Valerie Voigt, et al. Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1). J Pharm Pharmacol. 2013 Apr;65(4):582-90. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.5029 mL | 22.5144 mL | 45.0288 mL | 112.5720 mL |
| 5 mM | 0.9006 mL | 4.5029 mL | 9.0058 mL | 22.5144 mL | |
| 10 mM | 0.4503 mL | 2.2514 mL | 4.5029 mL | 11.2572 mL | |
| 15 mM | 0.3002 mL | 1.5010 mL | 3.0019 mL | 7.5048 mL | |
| 20 mM | 0.2251 mL | 1.1257 mL | 2.2514 mL | 5.6286 mL | |
| 25 mM | 0.1801 mL | 0.9006 mL | 1.8012 mL | 4.5029 mL | |
| 30 mM | 0.1501 mL | 0.7505 mL | 1.5010 mL | 3.7524 mL | |
| 40 mM | 0.1126 mL | 0.5629 mL | 1.1257 mL | 2.8143 mL | |
| 50 mM | 0.0901 mL | 0.4503 mL | 0.9006 mL | 2.2514 mL | |
| 60 mM | 0.0750 mL | 0.3752 mL | 0.7505 mL | 1.8762 mL | |
| 80 mM | 0.0563 mL | 0.2814 mL | 0.5629 mL | 1.4072 mL | |
| 100 mM | 0.0450 mL | 0.2251 mL | 0.4503 mL | 1.1257 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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