606143-89-9
606143-89-9
Chemical Structure
Binimetinib
Synonym(s): MEK162; ARRY-162; ARRY-438162
- CAS No.: 606143-89-9
- Formula:C17H15BrF2N4O3
- Molecular Weight:441.23
IUPAC Name: 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzo[d]imidazole-6-carboxamide
InChIKey: ACWZRVQXLIRSDF-UHFFFAOYSA-N
SMILES: BrC1=CC=C(C(F)=C1)NC2=C(C3=C(C=C2C(NOCCO)=O)N(C=N3)C)F
Biological Activity: Binimetinib (MEK162) is an oral and selective MEK1/2 inhibitor. Binimetinib (MEK162) inhibits MEK with an IC50 of 12 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Binimetinib | 99.92% | Binimetinib (MEK162) is an oral and selective MEK1/2 inhibitor. Binimetinib (MEK162) inhibits MEK with an IC50 of 12 nM. | ||||||||||||||||||||
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Binimetinib (Standard) | ≥98% | Binimetinib (Standard) is the analytical standard of Binimetinib. This product is intended for research and analytical applications. Binimetinib (MEK162) is an oral and selective MEK1/2 inhibitor. Binimetinib (MEK162) inhibits MEK with an IC50 of 12 nM. | ||||||||||||||||||||
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Binimetinib-d4 | Binimetinib-d4 (MEK162-d4) is deuterium labeled Binimetinib. Binimetinib (MEK162) is an oral and selective MEK1/2 inhibitor. Binimetinib (MEK162) inhibits MEK with an IC50 of 12 nM. | |||||||||||||||||||||
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Binimetinib-d3 | Binimetinib-d3 (MEK162-d3) is deuterium labeled Binimetinib. Binimetinib (MEK162) is an oral and selective MEK1/2 inhibitor. Binimetinib (MEK162) inhibits MEK with an IC50 of 12 nM. | |||||||||||||||||||||
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