6106-04-3
Chemical Structure
L-Glutamic acid monosodium hydrate
- CAS No.: 6106-04-3
- Formula:C5H10NNaO5
- Molecular Weight:187.13
IUPAC Name: sodium (S)-2-amino-4-carboxybutanoate hydrate
InChIKey: GJBHGUUFMNITCI-QTNFYWBSSA-M
SMILES: O=C([C@H](CCC(O)=O)N)O[Na].O
Biological Activity: L-Glutamic acid monosodium hydrate is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid monosodium hydrate has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid monosodium hydrate can be used in the study of neurological diseases. L-Glutamic acid monosodium hydrate acts at ionotropic and?metabotropic glutamate receptors[1][2][3][4][5].
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L-Glutamic acid monosodium hydrate | 98.0% | L-Glutamic acid monosodium hydrate is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid monosodium hydrate has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid monosodium hydrate can be used in the study of neurological diseases. L-Glutamic acid monosodium hydrate acts at ionotropic and?metabotropic glutamate receptors. | ||||||||||||||||||||
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Similarity Score 0.93
HY-W016145SL-Glutamic acid-13C5 hydrate salt -
Similarity Score 0.90
HY-14608AL-Glutamic acid monosodium salt -
Similarity Score 0.90
HY-W250122Glutamic acid sodium salt -
Similarity Score 0.86
HY-W015425H-Glu-OMe -
Similarity Score 0.85
HY-W140900Sodium (S)-3-amino-3-carboxypropanoate hydrate -
Similarity Score 0.85
HY-W010108DL-Glutamic acid hydrate -
Similarity Score 0.84
HY-Z3384RPemetrexed impurity 25 (Standard) -
Similarity Score 0.83
HY-W141949L-Glutamic acid potassium salt monohydrate -
Similarity Score 0.83
HY-100805S2D-Glutamic acid-13C5 -
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References
- [1]. Liberatore F, et al. Permissive role for mGlu1 metabotropic glutamate receptors in excitotoxic retinal degeneration. Neuroscience. 2017 Nov 5;363:142-149. [Content Brief]
- [2]. Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6(1):73-7. [Content Brief]
- [3]. Boga Pekmezekmek A, et al. L-Glutamic acid monosodium salt reduces the harmful effect of lithium on the development of Xenopus laevis embryos. Environ Sci Pollut Res Int. 2020 Nov;27(33):42124-42132. [Content Brief]
- [4]. Croce N, et al. Hydrochloric acid alters the effect of L-glutamic acid on cell viability in human neuroblastoma cell cultures. J Neurosci Methods. 2013 Jul 15;217(1-2):26-30. [Content Brief]
- [5]. Salyha N, et al. Protective role of l-glutamic acid and l-cysteine in mitigation the chlorpyrifos-induced oxidative stress in rats. Environ Toxicol Pharmacol. 2018 Dec;64:155-163. [Content Brief]