629-13-0
Chemical Structure
Azide-C2-Azide
- CAS No.: 629-13-0
- Formula:C2H4N6
- Molecular Weight:112.09
IUPAC Name: 1,2-diazidoethane
InChIKey: FEJUFSSWIQWAOC-UHFFFAOYSA-N
SMILES: [N-]=[N+]=NCCN=[N+]=[N-]
Biological Activity: Azide-C2-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azide-C2-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Azide-C2-Azide | Azide-C2-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azide-C2-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords