62929-91-3
62929-91-3
Chemical Structure
Procaterol hydrochloride
- CAS No.: 62929-91-3
- Formula:C16H23ClN2O3
- Molecular Weight:326.82
IUPAC Name: 8-hydroxy-5-((1S,2R)-1-hydroxy-2-(isopropylamino)butyl)quinolin-2(1H)-one hydrochloride
InChIKey: AEQDBKHAAWUCMT-KKJWGQAZSA-N
SMILES: O=C1NC2=C(C([C@H](O)[C@H](NC(C)C)CC)=CC=C2O)C=C1.[H]Cl
Biological Activity: Procaterol hydrochloride is a selective intermediate-acting β2 adrenoreceptor agonist with an EC50 of 12.9 μM[1]. Procaterol hydrochloride can inhibit inflammation both in vivo and in vitro[2].
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Procaterol hydrochloride | 99.99% | Procaterol hydrochloride is a selective intermediate-acting β2 adrenoreceptor agonist with an EC50 of 12.9 μM. Procaterol hydrochloride can inhibit inflammation both in vivo and in vitro. | ||||||||||||||||||||
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Procaterol-d7 hydrochloride | Procaterol-d7 hydrochloride is the deuterium labeled Procaterol hydrochloride (HY-100704). Procaterol is an oral selective β2 adrenergic receptor agonist. Procaterol inhibits eosinophil migration and the release of eosinophil chemotactic factor from BEAS-2B cells through a cyclic AMP-dependent mechanism. Procaterol has a large dose difference existing between the bronchodilator effect and the anabolic effect in rat, can be used for asthma research in athletes. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-100704A(Rac)-Procaterol hydrochloride -
Similarity Score 0.98
HY-114732Procaterol -
Similarity Score 0.64
HY-12463Carmoterol hydrochloride -
Similarity Score 0.64
HY-12463ACarmoterol -
Similarity Score 0.64
HY-B1481BIsoetharine hydrochloride -
Similarity Score 0.62
HY-B1481AIsoetharine -
Similarity Score 0.62
HY-U00293ZK-90055 hydrochloride -
Similarity Score 0.61
HY-B1481Isoetharine mesylate -
Similarity Score 0.58
HY-14299Indacaterol -
Explore the MedChemAI to find more analogs
References
- [1]. C Atgié, et al. Role of beta1- and beta3-adrenoceptors in the regulation of lipolysis and thermogenesis in rat brown adipocytes. Am J Physiol. 1997 Oct;273(4):C1136-42. [Content Brief]
- [2]. Zheng Deng, et al. Procaterol but not dexamethasone protects 16HBE cells from H2O2-induced oxidative stress. J Pharmacol Sci. 2014;125(1):39-50. [Content Brief]
