6314-70-1
6314-70-1
Chemical Structure
INK4C-IN-2
- CAS No.: 6314-70-1
- Formula:C13H17NO4S
- Molecular Weight:283.34
IUPAC Name: 4-(N-cyclohexylsulfamoyl)benzoic acid
InChIKey: XGOXPTXOQXHIDL-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(S(=O)(NC2CCCCC2)=O)C=C1
Biological Activity: INK4C-IN-2 is a p18INK4C inhibitor. NK4C-IN-2 promotes hematopoietic stem cells (HSCs) division by inhibiting INK4C and activating CDK4/6, with an ED50 of 5.21 nM. INK4C-IN-2 shows no cytotoxic to normal 32D cells, HSCs, leukemia cell lines and myeloma cell lines[1].
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INK4C-IN-2 | 98.35% | INK4C-IN-2 is a p18INK4C inhibitor. NK4C-IN-2 promotes hematopoietic stem cells (HSCs) division by inhibiting INK4C and activating CDK4/6, with an ED50 of 5.21 nM. INK4C-IN-2 shows no cytotoxic to normal 32D cells, HSCs, leukemia cell lines and myeloma cell lines. | ||||||||||||||||||||
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