6314-70-1

INK4C-IN-2 Chemical Structure
6314-70-1

Chemical Structure

INK4C-IN-2

  • CAS No.: 6314-70-1
  • Formula:C13H17NO4S
  • Molecular Weight:283.34

IUPAC Name: 4-(N-cyclohexylsulfamoyl)benzoic acid

InChIKey: XGOXPTXOQXHIDL-UHFFFAOYSA-N

SMILES: O=C(O)C1=CC=C(S(=O)(NC2CCCCC2)=O)C=C1

Biological Activity: INK4C-IN-2 is a p18INK4C inhibitor. NK4C-IN-2 promotes hematopoietic stem cells (HSCs) division by inhibiting INK4C and activating CDK4/6, with an ED50 of 5.21 nM. INK4C-IN-2 shows no cytotoxic to normal 32D cells, HSCs, leukemia cell lines and myeloma cell lines[1].

Cat. No. Product Name Purity Description Pricing
HY-108420 		INK4C-IN-2 98.10% INK4C-IN-2 is a p18INK4C inhibitor. NK4C-IN-2 promotes hematopoietic stem cells (HSCs) division by inhibiting INK4C and activating CDK4/6, with an ED50 of 5.21 nM. INK4C-IN-2 shows no cytotoxic to normal 32D cells, HSCs, leukemia cell lines and myeloma cell lines.
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