64000-73-3
64000-73-3
Chemical Structure
Pildralazine
Synonym(s): Propyldazine
- CAS No.: 64000-73-3
- Formula:C8H15N5O
- Molecular Weight:197.24
IUPAC Name: (E)-1-((6-hydrazono-1,6-dihydropyridazin-3-yl)(methyl)amino)propan-2-ol
InChIKey: KYIAWOXNPBANEW-UHFFFAOYSA-N
SMILES: CC(O)CN(C(C=C/1)=NNC1=N\N)C
Biological Activity: Pildralazine (Propyldazine) is a hydralazinelike antihypertensive vasodilator containing a free hydrazine group. Pildralazine is orally active, has no significant carcinogenicity in mice model[1][2].
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Pildralazine | Pildralazine (Propyldazine) is a hydralazinelike antihypertensive vasodilator containing a free hydrazine group. Pildralazine is orally active, has no significant carcinogenicity in mice model. | |||||||||||||||||||||
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References
- [1]. Della Porta G, Dragani TA. Carcinogenicity study in mice on pildralazine, a hydralazinelike antihypertensive compound. J Cancer Res Clin Oncol. 1983;106(2):97-101. [Content Brief]
- [2]. Chevillard C, et al. Interactions between hydralazine, propildazine and purines on arterial smooth muscle. Br J Pharmacol. 1981 Aug;73(4):811-7. [Content Brief]
