65132-74-3
Chemical Structure
A924
- CAS No.: 65132-74-3
- Formula:C30H57N7O11
- Molecular Weight:691.81
IUPAC Name: (S)-15-(bis(((butoxycarbonyl)amino)methyl)amino)-9-(((butoxycarbonyl)amino)methyl)-6,10-dioxo-5-oxa-7,9,11-triazahexadecan-16-oic acid
InChIKey: TUWMBEXKRLHQRM-DEOSSOPVSA-N
SMILES: CCCCOC(NCN(CNC(OCCCC)=O)C(NCCC[C@@H](C(O)=O)N(CNC(OCCCC)=O)CNC(OCCCC)=O)=O)=O
Biological Activity: A 924 is an amino acid derivative-based, orally active antitumor agent. A 924 is effective in inhibiting ascites tumors in rat models by intraperitoneal injection or oral administration. The LD50 of A 924 in mice is >1.5 g/kg and >4.5 g/kg by intraperitoneal injection or oral administration, respectively. A 924 does not cause teratogenicity or adverse reactions in normal or pregnant mice[1].
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A924 | A 924 is an amino acid derivative-based, orally active antitumor agent. A 924 is effective in inhibiting ascites tumors in rat models by intraperitoneal injection or oral administration. The LD50 of A 924 in mice is >1.5 g/kg and >4.5 g/kg by intraperitoneal injection or oral administration, respectively. A 924 does not cause teratogenicity or adverse reactions in normal or pregnant mice. | |||||||||||||||||||||
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Keywords
