667402-44-0
667402-44-0
Chemical Structure
BMS-577098
- CAS 番号: 667402-44-0
- Formula:C28H33ClN6O3
- Molecular Weight:537.05
IUPAC Name: (S)-4-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)-3-(6-(4-(2-methoxyethyl)piperazin-1-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one
InChIKey: UQNVJOYCOQUVLD-XMMPIXPASA-N
SMILES: COCCN(CC1)CCN1C2=CC(C)=C(N=C(C3=C(NC[C@@H](O)C4=CC=CC(Cl)=C4)C=CNC3=O)N5)C5=C2
Biological Activity: BMS-577098 is an orally active and ATP-competitive insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 0.016 μM. BMS-577098 shows anti-tumor effect[1].
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BMS-577098 | BMS-577098 is an orally active and ATP-competitive insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 0.016 μM. BMS-577098 shows anti-tumor effect. | |||||||||||||||||||||
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