67082-01-3
67082-01-3
Chemical Structure
MAO-B-IN-47
- CAS No.: 67082-01-3
- Formula:C16H13F3O
- Molecular Weight:278.27
IUPAC Name: 3-phenyl-1-(3-(trifluoromethyl)phenyl)propan-1-one
InChIKey: BOKMVXWUMBDRMJ-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C(F)(F)F)=CC=C1)CCC2=CC=CC=C2
Biological Activity: MAO-B-IN-47 is a selective monoamine oxidase B (MAO-B) inhibitor with a Ki of 875 nM. MAO-B-IN-47 shows an IC50 >100 μM for SH-SY5Y cells. MAO-B-IN-47 shows neuroprotective effect in 6-OHDA-treated SH-SY5Y cells. MAO-B-IN-47 can be used for the research of neurological disease, such as Parkinson’s disease (PD)[1].
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MAO-B-IN-47 | MAO-B-IN-47 is a selective monoamine oxidase B (MAO-B) inhibitor with a Ki of 875 nM. MAO-B-IN-47 shows an IC50 >100 μM for SH-SY5Y cells. MAO-B-IN-47 shows neuroprotective effect in 6-OHDA-treated SH-SY5Y cells. MAO-B-IN-47 can be used for the research of neurological disease, such as Parkinson’s disease (PD). | |||||||||||||||||||||
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References
Keywords
