67262-86-6
67262-86-6
Chemical Structure
Tn antigen
Synonym(s): GalNAcα-O-Ser
- CAS No.: 67262-86-6
- Formula:C11H20N2O8
- Molecular Weight:308.29
IUPAC Name: O-((2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-L-serine
InChIKey: REDMNGDGDYFZRE-WKWISIMFSA-N
SMILES: O[C@@H]([C@H]1O)[C@@H](NC(C)=O)[C@@H](OC[C@H](N)C(O)=O)O[C@@H]1CO
Biological Activity: Tn Antigen (Tn Epitope) (Compound 1) is a Trypanosoma cruzi trans-sialidase (TcTS) inhibitor with inhibition rate of 57% at 1 mM. Tn Antigen shows anti-trypanosomal activity with an IC50 of >0.5 mM. Tn Antigen can be used for the research of Chagas’ disease[1].
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Tn antigen | Tn Antigen (Tn Epitope) (Compound 1) is a Trypanosoma cruzi trans-sialidase (TcTS) inhibitor with inhibition rate of 57% at 1 mM. Tn Antigen shows anti-trypanosomal activity with an IC50 of >0.5 mM. Tn Antigen can be used for the research of Chagas’ disease. | |||||||||||||||||||||
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