681173-76-2
681173-76-2
Chemical Structure
ROCK2-IN-8
- CAS No.: 681173-76-2
- Formula:C17H13N3O3S
- Molecular Weight:339.37
IUPAC Name: N-(4-(pyridin-4-yl)thiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide
InChIKey: QKKGSTFAKMXWFE-UHFFFAOYSA-N
SMILES: O=C(C1OC2=C(OC1)C=CC=C2)NC3=NC(C4=CC=NC=C4)=CS3
Biological Activity: ROCK2-IN-8 (Compound 1) is an orally active ROCK2 inhibitor, with an IC50 of 7.2 nM. ROCK2-IN-8 can be used for the research of aqueous humor outflow in porcine eyes and myosin light chain phosphorylation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ROCK2-IN-8 | 99.85% | ROCK2-IN-8 (Compound 1) is an orally active ROCK2 inhibitor, with an IC50 of 7.2 nM. ROCK2-IN-8 can be used for the research of aqueous humor outflow in porcine eyes and myosin light chain phosphorylation. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.63
HY-47821WAY-655978 -
Similarity Score 0.60
HY-Q22471ROCK1-IN-1 -
Similarity Score 0.60
HY-15755RKI-1447 -
Similarity Score 0.59
HY-107209RKI-1313 -
Similarity Score 0.59
HY-110339RKI-1447 dihydrochloride -
Similarity Score 0.59
HY-153011ROCK-IN-5 -
Similarity Score 0.57
HY-148730BRD7586 -
Similarity Score 0.56
HY-48289PKA/AKAP-IN-2 -
Similarity Score 0.55
HY-100746STF-62247 -
Explore the MedChemAI to find more analogs
