690690-72-3
690690-72-3
Chemical Structure
GPD-1116
- CAS No.: 690690-72-3
- Formula:C22H16N4O
- Molecular Weight:352.39
InChIKey: NOZMPLJNURLIAQ-UHFFFAOYSA-N
SMILES: O=C1C2=C(C3=C(N1C4=CC=CC=C4)N=CC=C3)NN=C2CC5=CC=CC=C5
Biological Activity: GPD-1116 is an orally active Phosphodiesterase (PDE) 4 and PDE1 inhibitor. GPD-1116 can reduce smoke-induced apoptosis of lung cells. GPD-1116 is effective in several disease models in animals, including emphysema, acute lung injury, chronic obstructive pulmonary disease (COPD), asthma and pulmonary hypertension[1].
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GPD-1116 | GPD-1116 is an orally active Phosphodiesterase (PDE) 4 and PDE1 inhibitor. GPD-1116 can reduce smoke-induced apoptosis of lung cells. GPD-1116 is effective in several disease models in animals, including emphysema, acute lung injury, chronic obstructive pulmonary disease (COPD), asthma and pulmonary hypertension. | |||||||||||||||||||||
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