69367-51-7
69367-51-7
Chemical Structure
(R)-5-OH-DPAT
Synonym(s): (R)-5-Hydroxy-DPAT
- CAS No.: 69367-51-7
- Formula:C16H25NO
- Molecular Weight:247.38
InChIKey: MDBWEQVKJDMEMK-CQSZACIVSA-N
SMILES: OC1=CC=CC2=C1CC[C@H](C2)N(CCC)CCC
Biological Activity: (R)-5-OH-DPAT ((R)-5-Hydroxy-DPAT) is the R-enantiomer of 5-OH-DPAT (HY-131531A). 5-OH-DPAT is a weak antagonist of the dopamine D2 receptor (dopamine D2-receptor). 5-OH-DPAT moderately promotes sexual behavior in male rats[1][2].
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(R)-5-OH-DPAT | (R)-5-OH-DPAT ((R)-5-Hydroxy-DPAT) is the R-enantiomer of 5-OH-DPAT (HY-131531A). 5-OH-DPAT is a weak antagonist of the dopamine D2 receptor (dopamine D2-receptor). 5-OH-DPAT moderately promotes sexual behavior in male rats. | |||||||||||||||||||||
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References
- [1]. Ahlenius S, et al. Evidence for selective inhibition of limbic forebrain dopamine synthesis by 8-OH-DPAT in the rat. Naunyn Schmiedebergs Arch Pharmacol. 1989 May;339(5):551-6. [Content Brief]
- [2]. Karlsson A, et al. (R)- and (S)-5-hydroxy-2-(dipropylamino)tetralin (5-OH DPAT): assessment of optical purities and dopaminergic activities. Chirality. 1990;2(2):90-5. [Content Brief]
