69570-95-2
Chemical Structure
V-161
- CAS No.: 69570-95-2
- Formula:C16H17N3
- Molecular Weight:251.33
IUPAC Name: N,N-dimethyl-4-(6-methyl-1H-benzo[d]imidazol-2-yl)aniline
InChIKey: DCBQWCSRVVGWAN-UHFFFAOYSA-N
SMILES: CC1=CC2=C(C=C1)N=C(N2)C3=CC=C(C=C3)N(C)C
Biological Activity: V-161 is the orally active inhibitor for Na+-V-ATPase with an IC50 of 144 nM. V-161 inhibits Enterococcus hirae and Vancomycin-resistant Enterococcus faecium (VRE) under alkaline condition with MIC of 4 µg/mL and 4 µg/mL. V-161 inhibits colonization of VRE in mouse small intestine[1].
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V-161 | V-161 is the orally active inhibitor for Na+-V-ATPase with an IC50 of 144 nM. V-161 inhibits Enterococcus hirae and Vancomycin-resistant Enterococcus faecium (VRE) under alkaline condition with MIC of 4 µg/mL and 4 µg/mL. V-161 inhibits colonization of VRE in mouse small intestine. | |||||||||||||||||||||
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Keywords