69954-48-9
69954-48-9
Chemical Structure
β-CCM
Synonym(s): Beta-CCM; Ro 22-7497
- CAS No.: 69954-48-9
- Formula:C13H10N2O2
- Molecular Weight:226.23
IUPAC Name: methyl 9H-pyrido[3,4-b]indole-3-carboxylate
InChIKey: UKHFPVCOXBJPIN-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=C(C=N1)NC3=C2C=CC=C3)OC
Biological Activity: β-CCM is a benzodiazepine receptor inverse agonist with anxiogenic and proconvulsant effects. β-CCM enhances emotional reactivity and reduces vulnerability to interference in spatial working memory tasks. β-CCM can be used for research on anxiety-related disorders[1][2].
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β-CCM | 98.95% | β-CCM is a benzodiazepine receptor inverse agonist with anxiogenic and proconvulsant effects. β-CCM enhances emotional reactivity and reduces vulnerability to interference in spatial working memory tasks. β-CCM can be used for research on anxiety-related disorders. | ||||||||||||||||||||
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References
- [1]. Krazem A, et al. Effects of diazepam and beta-CCM on working memory in mice: relationships with emotional reactivity. Pharmacol Biochem Behav. 2001 Feb;68(2):235-44. [Content Brief]
- [2]. Chapouthier, G., et al. Comparison between the effects of the benzodiazepine receptor ligands methyl beta-carboline-3-carboxylate and diazepam in two learning situations in mice. Psychobiology 19, 58–63 (1991).
Keywords
