700874-71-1
700874-71-1
Chemical Structure
LY2109761
- CAS. Nr.: 700874-71-1
- Formula:C26H27N5O2
- Molecular Weight:441.52
IUPAC Name: 4-(2-((4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethyl)morpholine
InChIKey: IHLVSLOZUHKNMQ-UHFFFAOYSA-N
SMILES: N12N=C(C(C3=C4C=CC(OCCN5CCOCC5)=CC4=NC=C3)=C1CCC2)C6=NC=CC=C6
Biological Activity: LY2109761 is an orally active, selective TGF-β receptor type I/II inhibitor with Kis of 38 nM and 300 nM, respectively.
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LY2109761 | 99.72% | LY2109761 is an orally active, selective TGF-β receptor type I/II inhibitor with Kis of 38 nM and 300 nM, respectively. | ||||||||||||||||||||
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LY2109761 (Standard) | ≥98% | LY2109761 (Standard) is the analytical standard of LY2109761. This product is intended for research and analytical applications. LY2109761 is an orally active, selective TGF-β receptor type I/II inhibitor with Kis of 38 nM and 300 nM, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.76
HY-W028145TGF-βRI inhibitor 2 -
Similarity Score 0.71
HY-W684904LY550410 -
Similarity Score 0.64
HY-160237HYL001 -
Similarity Score 0.62
HY-13226AGalunisertib monohydrate -
Similarity Score 0.62
HY-13226RGalunisertib (Standard) -
Similarity Score 0.54
HY-110245DMH2 -
Similarity Score 0.52
HY-160215GFH018 -
Similarity Score 0.51
HY-182547LY580276 -
Similarity Score 0.51
HY-122105JNJ-40255293 -
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