70497-14-2
Chemical Structure
Teleocidin A1
Synonym(s): Lyngbyatoxin A
- CAS No.: 70497-14-2
- Formula:C27H39N3O2
- Molecular Weight:437.62
IUPAC Name: (2S,5S)-9-((R)-3,7-dimethylocta-1,6-dien-3-yl)-5-(hydroxymethyl)-2-isopropyl-1-methyl-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one
InChIKey: KISDGNGREAJPQR-OICBGKIFSA-N
SMILES: C/C(C)=C\CC[C@@](C)(C1=C2C3=C(C=C1)N([C@H](C(N[C@@H](CC3=CN2)CO)=O)C(C)C)C)C=C
Biological Activity: Teleocidin A1 (Lyngbyatoxin A) is a PKC activator with a Ki value of 0.11 nM for binding to the PKCδ-C1B peptide. Teleocidin A1 exhibits anticancer activity against cervical cancer and leukemia. Teleocidin A1 can induce seaweed dermatitis, food poisoning and local skin toxicity. Teleocidin A1 can be used in studies related to cervical cancer, seaweed dermatitis and food poisoning[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Teleocidin A1 | Teleocidin A1 (Lyngbyatoxin A) is a PKC activator with a Ki value of 0.11 nM for binding to the PKCδ-C1B peptide. Teleocidin A1 exhibits anticancer activity against cervical cancer and leukemia. Teleocidin A1 can induce seaweed dermatitis, food poisoning and local skin toxicity. Teleocidin A1 can be used in studies related to cervical cancer, seaweed dermatitis and food poisoning. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Youssef DT, et al. 2,3-seco-2,3-dioxo-lyngbyatoxin A from a Red Sea strain of the marine cyanobacterium Moorea producens. Nat Prod Res. 2015;29(8):703-9. [Content Brief]
- [2]. Jiang W, et al. Two new lyngbyatoxin derivatives from the Cyanobacterium, Moorea producens. Mar Drugs. 2014;12(12):5788-5800. Published 2014 Dec 1. [Content Brief]
- [3]. Stafford RG, et al. Comparison of the partition coefficient and skin penetration of a marine algal toxin (lyngbyatoxin A). Food Chem Toxicol. 1992;30(9):795-801. [Content Brief]
- [4]. Sakai S, Hitotsuyanagi Y, Aimi N, et al. Absolute configuration oOf lyngbyatoxin A (teleocidin A-1) and teleocidin A-2[J]. Tetrahedron letters, 1986, 27(43): 5219-5220.
Keywords
