71097-83-1
71097-83-1
Chemical Structure
Nileprost
- CAS No.: 71097-83-1
- Formula:C22H33NO5
- Molecular Weight:391.50
IUPAC Name: (E)-5-cyano-5-((3aR,4R,5R,6aS)-5-hydroxy-4-((3S,E)-3-hydroxy-4-methyloct-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-ylidene)pentanoic acid
InChIKey: OJIGXQJDLFUVFM-MBLRWRSDSA-N
SMILES: CCCCC(C)[C@H](O)/C=C/[C@@H]1[C@]2([H])[C@@](C[C@H]1O)([H])O/C(C2)=C(C#N)\CCCC(O)=O
Biological Activity: Nileprost is a prostacyclin analogue. Nileprost is a mixed type PGI2/PGE2 agonist. Nileprost can be studied in research on acute myocardial ischemia[1][2].
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Nileprost | Nileprost is a prostacyclin analogue. Nileprost is a mixed type PGI2/PGE2 agonist. Nileprost can be studied in research on acute myocardial ischemia. | |||||||||||||||||||||
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References
- [1]. Yoneda, M., & Ohkawa, Y. (1990). Degradation and isomerization of nileprost, 5-cyano-16-methyl-prostacyclin, in aqueous solution. Chemical & pharmaceutical bulletin, 38(9), 2507-2512. [Content Brief]
- [2]. Darius, H., et al., (1987). Cardiovascular actions in vitro and cardioprotective effects in vivo of nileprost, a mixed type PGI2/PGE2 agonist. Journal of cardiovascular pharmacology, 10(2), 144-152. [Content Brief]
