73121-56-9
Chemical Structure
Enprostil
Synonym(s): RS 84135
- CAS No.: 73121-56-9
- Formula:C23H28O6
- Molecular Weight:400.46
IUPAC Name: methyl 7-((1S,2S,3S)-3-hydroxy-2-((S,E)-3-hydroxy-4-phenoxybut-1-en-1-yl)-5-oxocyclopentyl)hepta-4,5-dienoate
InChIKey: PTOJVMZPWPAXER-FPXSIRDUSA-N
SMILES: O[C@H](COC1=CC=CC=C1)/C=C/[C@H]2[C@@H](C(C[C@@H]2O)=O)CC=C=CCCC(OC)=O
Biological Activity: Enprostil (RS 84135) is a prostaglandin E2 derivative. Enprostil can inhibit amogastrin-stimulated gastric acid secretion, as well as reducing the secretion of pepsin. Enprostil can also serve as an antiulcer agent, used for research of duodenal or gastric ulcers[1][2].
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Enprostil | Enprostil (RS 84135) is a prostaglandin E2 derivative. Enprostil can inhibit amogastrin-stimulated gastric acid secretion, as well as reducing the secretion of pepsin. Enprostil can also serve as an antiulcer agent, used for research of duodenal or gastric ulcers. | |||||||||||||||||||||
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- [1]. Kohli Y, et al. Antisecretory effect of a PGE2 derivative, enprostil (TA/RS-84135): inhibitory action of amogastrin-stimulated secretion. Drugs Exp Clin Res. 1988;14(11):673-8. [Content Brief]
- [2]. Goa K L, et al. Enprostil: a preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of peptic ulcer disease[J]. Drugs, 1987, 34(5): 539-559.
Keywords
