74515-39-2
74515-39-2
Chemical Structure
LY125180
- CAS No.: 74515-39-2
- Formula:C18H24ClNO
- Molecular Weight:305.84
IUPAC Name: N,N-dimethyl-1-phenyl-3-(p-tolyloxy)propan-1-amine hydrochloride
InChIKey: XLPKFDWDLKTMQZ-UHFFFAOYSA-N
SMILES: CC1=CC=C(OCCC(C2=CC=CC=C2)N(C)C)C=C1.[H]Cl
Biological Activity: LY125180 is a serotonin uptake inhibitor. LY125180 competitively inhibits the uptake of serotonin and norepinephrine by cortical synaptosomes and of dopamine by striatal synaptosomes, with Ki values of 0.06 μM, 2.2 μM and 2.5 μM respectively[1].
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LY125180 | LY125180 is a serotonin uptake inhibitor. LY125180 competitively inhibits the uptake of serotonin and norepinephrine by cortical synaptosomes and of dopamine by striatal synaptosomes, with Ki values of 0.06 μM, 2.2 μM and 2.5 μM respectively. | |||||||||||||||||||||
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References
Keywords
