757183-18-9
757183-18-9
Chemical Structure
NNC 38-1049
- CAS No.: 757183-18-9
- Formula:C19H25ClN2O2
- Molecular Weight:348.87
IUPAC Name: 1-(4-chlorophenyl)-4-(4-cyclopentylpiperazin-1-yl)butane-1,4-dione
InChIKey: VPARRMQGLNFBBR-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(Cl)C=C1)CCC(N2CCN(C3CCCC3)CC2)=O
Biological Activity: NNC 38-1049 is an orally active, potent and competitive histamine H3 receptor antagonist. NNC 38-1049 produced an increase in extracellular levels of histamine in the paraventricular nucleus. NNC 38-1049 decreases food intake and body weight, which is promising for research of obesity[1].
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NNC 38-1049 | 99.84% | NNC 38-1049 is an orally active, potent and competitive histamine H3 receptor antagonist. NNC 38-1049 produced an increase in extracellular levels of histamine in the paraventricular nucleus. NNC 38-1049 decreases food intake and body weight, which is promising for research of obesity. | ||||||||||||||||||||
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References
Keywords
