75808-66-1
Chemical Structure
LVV-hemorphin-7
- CAS No.: 75808-66-1
- Formula:C65H93N15O14
- Molecular Weight:1308.53
InChIKey: NBQSSMDPPLHNDC-GSOGOTFGSA-N
SMILES: O=C([C@H]1N(CCC1)C([C@@H](NC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@@H](N)CC(C)C)=O)=O)=O)CC2=CC=C(C=C2)O)=O)N[C@H](C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)CC4=CNC5=CC=CC=C45
Biological Activity: LVV-hemorphin-7 is an Angiotensin IV receptor ligand and IRAP inhibitor (IC50s: 17.6 nM for sheep adrenal IRAP; 5.0 nM for sheep cerebellum IRAP). LVV-hemorphin-7 inhibits the catalytic activity of IRAP. LVV-hemorphin-7 stimulates DNA synthesis. LVV-hemorphin-7 elicits a number of physiological effects, including cellular proliferation and memory enhancement[1].
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LVV-hemorphin-7 | LVV-hemorphin-7 is an Angiotensin IV receptor ligand and IRAP inhibitor (IC50s: 17.6 nM for sheep adrenal IRAP; 5.0 nM for sheep cerebellum IRAP). LVV-hemorphin-7 inhibits the catalytic activity of IRAP. LVV-hemorphin-7 stimulates DNA synthesis. LVV-hemorphin-7 elicits a number of physiological effects, including cellular proliferation and memory enhancement. | |||||||||||||||||||||
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Keywords
