1. GPCR/G Protein Metabolic Enzyme/Protease Cell Cycle/DNA Damage
  2. Angiotensin Receptor Aminopeptidase DNA/RNA Synthesis
  3. LVV-hemorphin-7

LVV-hemorphin-7 is an Angiotensin IV receptor ligand and IRAP inhibitor (IC50s: 17.6 nM for sheep adrenal IRAP; 5.0 nM for sheep cerebellum IRAP). LVV-hemorphin-7 inhibits the catalytic activity of IRAP. LVV-hemorphin-7 stimulates DNA synthesis. LVV-hemorphin-7 elicits a number of physiological effects, including cellular proliferation and memory enhancement.

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LVV-hemorphin-7

LVV-hemorphin-7 Chemical Structure

CAS No. : 75808-66-1

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Description

LVV-hemorphin-7 is an Angiotensin IV receptor ligand and IRAP inhibitor (IC50s: 17.6 nM for sheep adrenal IRAP; 5.0 nM for sheep cerebellum IRAP). LVV-hemorphin-7 inhibits the catalytic activity of IRAP. LVV-hemorphin-7 stimulates DNA synthesis. LVV-hemorphin-7 elicits a number of physiological effects, including cellular proliferation and memory enhancement[1].

IC50 & Target[1]

Angiotensin IV Receptor

 

IRAP (sheep adrenal)

17.6 nM (IC50)

IRAP (sheep cerebellum )

5.0 nM (IC50)

Molecular Weight

1308.53

Formula

C65H93N15O14

CAS No.
Sequence

Leu-Val-Val-Tyr-Pro-Trp-Thr-Gln-Arg-Phe

Sequence Shortening

LVVYPWTQRF

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
LVV-hemorphin-7
Cat. No.:
HY-P11643
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