77174-66-4
Chemical Structure
710674-S
- CAS No.: 77174-66-4
- Formula:C18H16Cl2N2O
- Molecular Weight:347.24
IUPAC Name: 1-(1-(2-((3-chlorobenzyl)oxy)phenyl)vinyl)-1H-imidazole hydrochloride
InChIKey: LWJUIYYIILPRRI-UHFFFAOYSA-N
SMILES: ClC1=CC=CC(COC2=C(C(N3C=NC=C3)=C)C=CC=C2)=C1.Cl
Biological Activity: 710674-S is a synthetic imidazole derivative with antibacterial and antifungal activities. 710674-S exhibits potent activity against dermatophytes, and moderate activity against Candida species, other yeasts, Gram-positive aerobic bacteria and most anaerobic bacteria. 710674-S inhibits lanosterol 14α-demethylase (CYP51), a key enzyme in the fungal ergosterol biosynthetic pathway. The antifungal activity of 710674-S increases in alkaline culture media. 710674-S can be used in studies related to fungal infectious diseases[1].
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710674-S | 710674-S is a synthetic imidazole derivative with antibacterial and antifungal activities. 710674-S exhibits potent activity against dermatophytes, and moderate activity against Candida species, other yeasts, Gram-positive aerobic bacteria and most anaerobic bacteria. 710674-S inhibits lanosterol 14α-demethylase (CYP51), a key enzyme in the fungal ergosterol biosynthetic pathway. The antifungal activity of 710674-S increases in alkaline culture media. 710674-S can be used in studies related to fungal infectious diseases. | |||||||||||||||||||||
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Keywords
