7737-17-9
Chemical Structure
Aminoacetone hydrochloride
- CAS No.: 7737-17-9
- Formula:C3H8ClNO
- Molecular Weight:109.55
IUPAC Name: 1-aminopropan-2-one hydrochloride
InChIKey: RUCLDQBBIJKQHO-UHFFFAOYSA-N
SMILES: CC(CN)=O.Cl
Biological Activity: Aminoacetone hydrochloride is an α-aminoketone and also a catabolite of threonine and glycine. When accumulated under pathological conditions, Aminoacetone hydrochloride participates in oxidative damage and protein dysfunction via the production of reactive oxygen species (ROS) and methylglyoxal, and it is associated with phenotypes such as diabetes, mitochondrial damage and sleep disorders[1][2][3].
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Aminoacetone hydrochloride | 99.44% | Aminoacetone hydrochloride is an α-aminoketone and also a catabolite of threonine and glycine. When accumulated under pathological conditions, Aminoacetone hydrochloride participates in oxidative damage and protein dysfunction via the production of reactive oxygen species (ROS) and methylglyoxal, and it is associated with phenotypes such as diabetes, mitochondrial damage and sleep disorders. | ||||||||||||||||||||
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- [1]. Zhou S, et al. Aminoacetone is associated with sleep latency. Sleep Med. 2025;128:183-186. [Content Brief]
- [2]. Dutra F, et al. Aminoacetone induces iron-mediated oxidative damage to isolated rat liver mitochondria. Arch Biochem Biophys. 2004;430(2):284-289. [Content Brief]
- [3]. Ramos LD, et al. Aerobic co-oxidation of hemoglobin and aminoacetone, a putative source of methylglyoxal. Free Radic Biol Med. 2021;166:178-186. [Content Brief]
Keywords