Glycine-15N
Based on 1 Customer Validation
Glycine-15N is the 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
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- Reinheit: 99.95%
- CAS. Nr.: 7299-33-4
- Formel: C2H515NO2
- Molecular Weight:76.06
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Speicherung:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
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NMDA Receptor |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 7299-33-4
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Unlabeled Cas 56-40-6
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Appearance Solid
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Molecular Weight 76.06
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Formel C2H515NO2
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Color White to off-white
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SMILES
[15NH2]CC(O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Lösungsmittel & Löslichkeit
H2O : 23.33 mg/mL (306.73 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Johnson JW, et al. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature. 1987 Feb 5-11;325(6104):529-31. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 13.1475 mL | 65.7376 mL | 131.4752 mL | 328.6879 mL |
| 5 mM | 2.6295 mL | 13.1475 mL | 26.2950 mL | 65.7376 mL | |
| 10 mM | 1.3148 mL | 6.5738 mL | 13.1475 mL | 32.8688 mL | |
| 15 mM | 0.8765 mL | 4.3825 mL | 8.7650 mL | 21.9125 mL | |
| 20 mM | 0.6574 mL | 3.2869 mL | 6.5738 mL | 16.4344 mL | |
| 25 mM | 0.5259 mL | 2.6295 mL | 5.2590 mL | 13.1475 mL | |
| 30 mM | 0.4383 mL | 2.1913 mL | 4.3825 mL | 10.9563 mL | |
| 40 mM | 0.3287 mL | 1.6434 mL | 3.2869 mL | 8.2172 mL | |
| 50 mM | 0.2630 mL | 1.3148 mL | 2.6295 mL | 6.5738 mL | |
| 60 mM | 0.2191 mL | 1.0956 mL | 2.1913 mL | 5.4781 mL | |
| 80 mM | 0.1643 mL | 0.8217 mL | 1.6434 mL | 4.1086 mL | |
| 100 mM | 0.1315 mL | 0.6574 mL | 1.3148 mL | 3.2869 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Glycine-15N Related Classifications
HY-Y0966S Related Classifications
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