778270-11-4
778270-11-4
Chemical Structure
GNF-2
- CAS No.: 778270-11-4
- Formula:C18H13F3N4O2
- Molecular Weight:374.32
IUPAC Name: 3-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)benzamide
InChIKey: WEVYNIUIFUYDGI-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC(C2=CC(NC3=CC=C(OC(F)(F)F)C=C3)=NC=N2)=C1)N
Biological Activity: GNF-2 is a highly selective, allosteric, non-ATP competitive inhibitor of Bcr-Abl. GNF-2 inhibits Ba/F3.p210 proliferation with an IC50 of 138 nM [1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
GNF-2 | 99.82% | GNF-2 is a highly selective, allosteric, non-ATP competitive inhibitor of Bcr-Abl. GNF-2 inhibits Ba/F3.p210 proliferation with an IC50 of 138 nM . | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
GNF-2 (Standard) | ≥98% | GNF-2 (Standard) is the analytical standard of GNF-2. This product is intended for research and analytical applications. GNF-2 is a highly selective, allosteric, non-ATP competitive inhibitor of Bcr-Abl. GNF-2 inhibits Ba/F3.p210 proliferation with an IC50 of 138 nM . | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.89
HY-161805GNF-2-acid -
Similarity Score 0.89
HY-111852GNF5-amido-Me -
Similarity Score 0.84
HY-15738GNF-5 -
Similarity Score 0.76
HY-130297PROTAC BCR-ABL1 ligand 1 -
Similarity Score 0.74
HY-103032Multi-kinase inhibitor 1 -
Similarity Score 0.71
HY-135634GNF-2-PEG-acid -
Similarity Score 0.58
HY-145887BCR-ABL1-IN-1 -
Similarity Score 0.58
HY-100870Obefazimod -
Similarity Score 0.57
HY-161807DENV ligand 1 -
Explore the MedChemAI to find more analogs
