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Cat. No.: HY-161805

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GNF-2-acid

GNF-2-acid is a target protein ligand activity control that can be used for the synthesis of PROTACs (HY-161806) .

For research use only. We do not sell to patients.

CAS No.: 714962-05-7
Formula: C₁₈H₁₂F₃N₃O₃
Molecular Weight:375.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

GNF-2-acid Chemical Structure

CAS No.: 714962-05-7

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Quantity

Sample (0.1mg)

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(In Japan)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

GNF-2-acid is a target protein ligand activity control that can be used for the synthesis of PROTACs (HY-161806) ^[1].

Chemical Information

CAS No. 714962-05-7
Molecular Weight 375.30
Formula C₁₈H₁₂F₃N₃O₃
SMILES

O=C(O)C1=CC=CC(C2=CC(NC3=CC=C(OC(F)(F)F)C=C3)=NC=N2)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liu HY, et al. Broad-spectrum activity against mosquito-borne flaviviruses achieved by a targeted protein degradation mechanism. Nat Commun. 2024 Jun 19;15(1):5179. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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