779-27-1
Chemical Structure
3-Carboxy-7-Hydroxycoumarin
- CAS No.: 779-27-1
- Formula:C10H6O5
- Molecular Weight:206.15
IUPAC Name: 7-hydroxy-2-oxo-2H-chromene-3-carboxylic acid
InChIKey: LKLWLDOUZJEHDY-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=CC=C(O)C=C2OC1=O)O
Biological Activity: 3-Carboxy-7-Hydroxycoumarin is a 7-hydroxycoumarin (umbelliferone) fluorescent dye and antibody-conjugated labeling agent with UV excitation properties. 3-Carboxy-7-Hydroxycoumarin undergoes deprotonation in neutral-to-alkaline environments, producing strong blue fluorescence. The absorption/emission maxima of 3-Carboxy-7-Hydroxycoumarin are 386/448 nm. 3-Carboxy-7-Hydroxycoumarin is applicable for related research such as fluorescent probe synthesis and covalent protein labeling[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3-Carboxy-7-Hydroxycoumarin | 99.10% | 3-Carboxy-7-Hydroxycoumarin is a 7-hydroxycoumarin (umbelliferone) fluorescent dye and antibody-conjugated labeling agent with UV excitation properties. 3-Carboxy-7-Hydroxycoumarin undergoes deprotonation in neutral-to-alkaline environments, producing strong blue fluorescence. The absorption/emission maxima of 3-Carboxy-7-Hydroxycoumarin are 386/448 nm. 3-Carboxy-7-Hydroxycoumarin is applicable for related research such as fluorescent probe synthesis and covalent protein labeling. | ||||||||||||||||||||
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References
- [1]. Abrams B, et al. 3-Carboxy-6-chloro-7-hydroxycoumarin: a highly fluorescent, water-soluble violet-excitable dye for cell analysis. Analytical biochemistry. 2009 Mar 15;386(2):262-9.
- [2]. Sun WC, et al. Synthesis of novel fluorinated coumarins: excellent UV-light excitable fluorescent dyes. Bioorganic & medicinal chemistry letters. 1998 Nov 17;8(22):3107-10. [Content Brief]
