77946-49-7
77946-49-7
Chemical Structure
AF-CX 921
- CAS No.: 77946-49-7
- Formula:C15H11NOS
- Molecular Weight:253.32
IUPAC Name: (E)-2-(amino(phenyl)methylene)benzo[b]thiophen-3(2H)-one
InChIKey: XIJTZTNNGQLXAT-FYWRMAATSA-N
SMILES: O=C1C2=CC=CC=C2S/C1=C(N)\C3=CC=CC=C3
Biological Activity: AF-CX 921 is an orally active anticonvulsant agent. AF-CX 921 exhibits antiepileptic effects in ferrets, hippocampally kindled cats, and Mongolian gerbils. AF-CX 921 exhibits anticonvulsant activity in normal and microcephalic hippocampally kindled rats. AF-CX 921 can be used for the research of epileptic seizures and epilepsy[1][2].
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AF-CX 921 | AF-CX 921 is an orally active anticonvulsant agent. AF-CX 921 exhibits antiepileptic effects in ferrets, hippocampally kindled cats, and Mongolian gerbils. AF-CX 921 exhibits anticonvulsant activity in normal and microcephalic hippocampally kindled rats. AF-CX 921 can be used for the research of epileptic seizures and epilepsy. | |||||||||||||||||||||
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References
- [1]. Majkowski J, et al. Effects of carbamazepine, AF-CX 921, and AF-CX 1325 on epileptic discharges and seizures in hippocampally kindled rats. Epilepsia. 1986 Jul-Aug;27(4):391-8. [Content Brief]
- [2]. Majkowski J, et al. Differences in antiepileptic drug efficacy in hippocampally kindled normal and microcephalic rats. Brain Res. 1986 Oct 29;386(1-2):325-31. [Content Brief]
