791826-72-7
791826-72-7
Chemical Structure
INCB3619
- CAS No.: 791826-72-7
- Formula:C22H27N3O5
- Molecular Weight:413.47
IUPAC Name: (6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-tetrahydropyridine-1-carbonyl)-5-azaspiro[2.5]octane-5-carboxylate
InChIKey: CKZHFOKQZRZCPF-ROUUACIJSA-N
SMILES: O=C(N([C@H](C(N1CC=C(C2=CC=CC=C2)CC1)=O)[C@@H](C(NO)=O)C3)CC43CC4)OC
Biological Activity: INCB3619 is a selective and orally active ADAM inhibitor with IC50 of 22 nM and 14 nM for ADAM10 and ADAM17, respectively. INCB3619 has anti-tumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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INCB3619 | 99.46% | INCB3619 is a selective and orally active ADAM inhibitor with IC50 of 22 nM and 14 nM for ADAM10 and ADAM17, respectively. INCB3619 has anti-tumor activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.73
HY-10293Aderbasib -
Similarity Score 0.51
HY-155813MPI60 -
Similarity Score 0.48
HY-178696UAWJ9-36-3 -
Similarity Score 0.48
HY-P4612Z-Pro-Pro -
Similarity Score 0.46
HY-134454Z-Pro-Pro-CHO -
Similarity Score 0.46
HY-134454AZ-Pro-prolinal -
Similarity Score 0.45
HY-P4308Z-Pro-Pro-aldehyde-dimethyl acetal -
Similarity Score 0.45
![[Phe2]-TRH Chemical Structure](//file.medchemexpress.com/product_pic/hy-p3962.gif)
HY-P3962[Phe2]-TRH -
Similarity Score 0.45
HY-P4611Z-Pro-Ala -
Explore the MedChemAI to find more analogs
![[Phe2]-TRH Chemical Structure](http://file.medchemexpress.com/product_pic/hy-p3962.gif)
