UAWJ9-36-3
UAWJ9-36-3 is a Mpro and cathepsin L (IC50: 1.81 μM) inhibitor. UAWJ9-36-3 shows potent binding and enzymatic inhibition against the Mpros from SARS-CoV-2, SARS-CoV, MERS-CoV, HCoV-OC43, HCoV-NL63, HCoV-229E, and HCoV-HKU1. UAWJ9-36-3 demonstrates broad-spectrum antiviral activity against not only SARS-CoV-2, but also the common human coronaviruses HCoV-OC43, HCoV-NL63, and HCoV-229E.
For research use only. We do not sell to patients.
- CAS No.: 2663864-31-9
- Formula: C23H29N3O5
- Molecular Weight:427.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Cathepsin Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
cathepsin L 1.81 μM (IC50) |
Chemical Information
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CAS No. 2663864-31-9
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Molecular Weight 427.49
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Formula C23H29N3O5
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SMILES
O=C(NCC1)[C@@H]1C[C@@H](C=O)NC(C2[C@]3([H])[C@@](CN2C(OCC4=CC=CC=C4)=O)([H])C3(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)